Essential Biochemistry - Hemoglobin Metabolism (Section 3 - No. 4)
The oxidation of protoporphyrin-IX to protoporphyrin-IX di-oxide is catalyzed by:
Heme oxygenase
Heme synthase
Uroporphyrinogen decarboxylase
Aminolevulinate dehydratase
Explanation
The oxidation of protoporphyrin-IX to protoporphyrin-IX di-oxide is catalyzed by heme oxygenase